Biodegradable and designed with “pharma-worthy” specificity to the intended target
© 2023 TRILLIUM AG
With the Agrisome platform, Trillium combines three novel biotechnologies within a single platform to solve some of the most critical challenges to RNAi in agriculture:
1 MV-RNA Trigger:
Three short, multivalent RNAi triggers arranged in a unique junction alignment with the potential for multi-gene silencing.
2 Nanoparticle Core:
Multiple MV-RNA are expressed in a single-stranded, self-forming nanostructure that improves specificity and potency.
3 Protein Shell:
The complete Agrisome encapsulates each nanoparticle in a protein ‘coat’ that protects it from degredation, overcomes various biological barriers to delivery, enables insect-specific targeting and activity, and adds other modes of action to its RNAi core.
Importantly, Agrisomes are designed for use as either sustainably biomanufactured topical treatments or expressed in-planta as traits. To learn more about the novel self-formulating characteristics of Trillium Agrisomes, click here.